hrp0092lb-10 | Late Breaking Posters | ESPE2019

Irisin as a Mediator between Obesity and Vascular Inflammation in Chinese Children and Adolescents

yin chunyan , xiao yanfeng

Objectives: The aim was to clarify the associations of Irisin with obesity and early onset metabolic and vascular sequelae in Chinese children, and to examine whether the association between obesity and endothelial dysfunction and vascular Inflammation was mediated by Irisin.Methods: We quantified Irisin serum levels in 85 lean and 120 obese children and assessed associations with metabolic and cardiovascular parameters ...